Dave Carney.jpg

Dave Carney, MD

Lab Years: 1998-2000

Fellowship: Pediatric Surgery

                                Riley Children's Hospital

(Critical Care Lab) Publications:

1.       Lutz CJ, Carney DE, Finck C, Picone A, Gatto LA,  Paskanik A, Langenback E, Nieman GF. Aerosolized surfactant improves pulmonary function in endotoxin-induced lung injury. Am J Resp Crit Care Med. 158:840-845, 1998.


2.       Carney DE, Bredenberg CE, Fillinger MF,  Schiller H, Picone AL, Nieman GF. The Alveolar recruitment-derecruitment is the primary mechanism by which lung volume changes during mechanical ventilation. Surgical Forum.  1998. 49:40-43.


3.       Picone AL, Lutz CJ, Finck C, Carney DE, Gatto LA, Paskanik A, Searles B, Synder K, Nieman GF. Multiple sequential insults cause post-pump syndrome. Ann Thorac Surg.  1999. 67:978-985.


4.       Lutz CJ, Carney DE, Picone AL, Schiller HJ, Gatto LA, Snyder K, Paskanik AM, Nieman GF.  Videomicroscopy provides accurate in vivo assessment of pulmonary microvascular reactivity in rabbits. Shock. 1999. 11:367-371. 


5.       Carney DE,  Lutz CJ, Picone A, Gatto LA, Schiller H, Finck C, Searles B, Paskanik A, Snyder K, Edwards C, Nieman GF. Soluble tumor necrosis factor receptor prevents post-pump syndromes. J Surg Res.  1999. 82: 113-121. 


6.       Carney DE, Lutz CJ, Picone A,  Gatto LA, Ramamurthy NS, Golub LM, Simon SR, Searles B,  Paskanik A, Snyder K, Finck C, Schiller H, Nieman GF. Matrix Metalloproteinase Inhibitor Prevents Acute Lung Injury after Cardiopulmonary Bypass. Circulation. 1999. 100:400-406.


7.       Carney DE, Bredenberg CE, Schiller HJ, Picone AL, McCann UG, Gatto LA, Bailey G, Fillinger M, Nieman GF. The Mechanism of Lung Volume Change during Mechanical Ventilation. Am J Resp Crit Care Med. 1999. 160:1697-1702.


8.       McCann UG, Gatto LA, Searles B, Carney DE, Picone A, Lutz CJ, Schiller HJ, Nieman GF. Matrix metalloproteinase inhibitor: Differential effects on pulmonary neutrophil and monocyte sequestration following cardiopulmonary bypass. J Extracorporeal Tech. 1999. 31(2):67-75.


9.       McCann UG, Schiller HJ, Carney DE, Gagne GM, Thomas D, Hellwig B, Gatto LA, Nieman GF. Alveolar recruitment as a mechanism of normal lung volume change: evidence from a novel nuclear imaging technique.  Surgical Forum. 1999. 50:155-157.


10.       Nieman GF, Searles B, Carney DE, McCann UG, Schiller HJ, Lutz CJ, Finck C, Gatto LA, Hodell M, Picone AL.  Systemic inflammation induced by cardiopulmonary bypass: a review of pathogenesis and treatment. J Extracorporeal Tech. 1999. 31:202-210.


11.       Schiller HJ, McCann UG, Carney DE, Gatto LA, Steinberg JM, Nieman GF. Altered alveolar mechanics in the acutely injured lung. Crit Care Med. 2001;29(5):1049-1055.


12.       Carney DE, McCann UG, Schiller HJ, Gatto LA, Steinberg JM, Picone AL, Nieman GF. Metalloproteinase inhibition prevents acute respiratory distress syndrome. J Surg Res. 2001. 99;245-252.


13.       McCann UG, Schiller HJ, Carney DE, Gatto LA, Steinberg JM, Nieman GF. Visual validation of the mechanical stabilizing effects of PEEP at the alveolar level (Mechanical Stabilizing effects of PEEP). J Surg Res. 2001. 99;335-342.


14.       McCann UG, Schiller HJ, Carney DE, Kilpatrick J, Gatto LA, Paskanik AM, Nieman GF. Invasive arterial blood pressure monitoring in trauma and critical care: effect of variable transducer level, catheter access and patient position.  Chest. 2001. 120; 1322-1326.


15.      McCann UG, Schiller HJ, Gatto LA, Steinberg JM, Carney DE, Nieman GF. Alveolar mechanics alter hypoxic pulmonary vasoconstriction. Crit Care Med. 2002. 30(6):1315-1321.

16.      Schiller HJ, Steinberg J, Halter JM, McCann UG, Dasilva M, Gatto LA, Carney DE, Nieman GF. Alveolar inflation during generation of a quasi-static pressure/volume curve in the acutely injured lung. Crit Care Med. 2003. 31:1126-1133.


17.      Carney DE, DiRocco J, Nieman GF. Dynamic alveolar mechanics and ventilator induced lung injury (VILI). Crit Care Medicine. 2005; 33 [Suppl]: S122-S128.

18.      Steinberg JM, Halter JM, Schiller H, Gatto LA, Carney DE, Lee H-M, Golub L, Nieman GF. Chemically-modified tetracycline (COL-3) prevents the development of septic shock and acute respiratory distress syndrome in a clinically applicable porcine model. Shock. 2005;24:348-356.


19.      DiRocco J, Pavone LA, Carney DE, Lutz CJ, Gatto LA, Landas SK, Nieman GF. Dynamic alveolar mechanics in four models of lung injury. Intensive Care Med. 2006;32:140-148.


20.      Pavone LA, DiRocco J, Carney DE, Gatto LA, McBride N-TD, Norton JA, Hession RM, Boubert F, Hojnowski KA,  LaFollette RL, Dries DJ, Nieman GF. Absence of Alveolar Tears in Rat Lungs with Significant Alveolar Instability. Respiration. 2007;74(4):439-446.


21.      Pavone LA, Albert SP, Carney DE, Gatto LA, Halter JM, Nieman GF. Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics. Crit Care. 2007;11:R64.


22.      LaFollette R, Hojnowski K, Norton J, DiRocco J, Carney DE, Nieman GF. Using the pressure volume (P/V) curve to set proper PEEP in acute lung injury. Nurs Crit Care. 2007;12(5): 231-241.


23.      Halter JM, Steinberg JM, Gatto LA, DiRocco J, Picone, LA, Schiller HJ, Albert SP, Lee H-M, Carney DE, Nieman GF. Effect of Positive End-expiratory Pressure (PEEP) and Tidal Volume on Alveolar Instability-Induced Lung Injury. Crit Care. 2007;11 (1):R20.


24.      DiRocco J, Carney DE, Nieman GF. Correlation of alveolar recruitment-derecruitment with inflection points on the pressure-volume curve. Intensive Care Med. 2007;33:1204-1211.