Shreyas Roy.jpg

Shreyas Roy, MD

Lab Years: 2010-2013

Fellowship: Pediatric Surgery (2016-2018)

                                Hospital Sainte Justine

(Critical Care Lab) Publications:

1.      Kubiak BD, Albert SP, Gatto LA, Snyder KP, Maier KG, Vieau CJ, Roy SK, Nieman GF. Peritoneal negative pressure therapy prevents multiple organ injury in a chronic porcine sepsis and ischemia/reperfusion model. Shock. 2010; 34(5):525-534.


2.      Maggio D, Sadowitz B , Vieau C, Albert SP, Kubiak BD, Roy SK, CM1, Gatto LA, Nieman GF. Titration of Mean Airway Pressure and FiO2 During High Frequency Oscillatory Ventilation in a Porcine Model of Acute Lung Injury. J Surg Res. 2010; 164:e146-e153.


3.      Kubiak BD, Albert SP, Gatto LA, Vieau CJ, Roy SK, Snyder KP, Maier KG, Nieman GF. A clinically applicable porcine model of septic and ischemia/reperfusion induced shock and multiple organ injury. J Surg Res. 2011; 166(1):e59-69.


4.      Albert SP, Kubiak BD, Vieau CJ, DiRocco J, Gatto LA, Young JL, Tripathi S, Roy SK, Trikha G, Lopez C, Nieman GF. Comparison of “open lung" models with low tidal volumes in a porcine lung injury model. J Surg Res. 2011;166(1):e71-81.


5.      Roy SK, Kendrick D, Sadowitz B, Gatto LA, Snyder K, Satalin J, Golub LM, Nieman GF. Jack of All Trades: Pleiotropy and the application of Chemically Modified Tetracycline -3 in Sepsis and the Acute Respiratory Distress Syndrome (ARDS). Pharmacological Research. 2011; 64: 580-589.


6.      Sadowitz B, Roy SK, Gatto LA, Habashi NM, Nieman GF. Lung injury induced by sepsis: lessons learned from large animal models and future directions for treatment. Expert Rev Anti Infect Ther. 2011 9(12):1169-78.


7.      Roy SK, Kubiak BD, Albert SP, Vieau C, Gatto LA, Golub L, Lee HM, Sookhu S, Vodovotz Y, Nieman GF. Chemically Modified Tetracycline-3 prevents ARDS in a Porcine Model of Sepsis+ Ischemia/reperfusion induced lung injury. Shock. 2012;37:424-32.


8.      Roy SK, Sadowitz B, Andrews PL, Kuhn M, Ghosh A, Gatto LA, Marx W, Dean D, Lin X, Wang G, Ge L, Vodovotz Y, Nieman GF, Habashi NM. Early stabilizing ventilation prevents acute respiratory distress syndrome: A novel timing-based ventilatory intervention to avert lung injury. J Trauma Acute Care Surg. 2012;73:391.

9.      Habashi NM, Andrews PL, Roy SK, Sadowitz B, Gatto LA, Nieman GF. Up in smoke: Airway pressure release ventilation must be applied correctly to protect the lung. Crit Care Med. 2012;40:1040.


10.      Roy SK, Habashi NM, Sadowitz B, Andrews PL, Ge L, Wang G, Roy P, Singh A, Ghosh A, Kuhn M, Satalin J, Gatto LA, Lin X, Dean D, Vodovotz Y, Nieman GF. Early airway pressure release ventilation prevents ARDS: A novel preventive approach to lung injury. Shock. 2013;30:28-38.


11.      Emr B, Gatto LA, Roy SK, Satalin J, Ghosh A, Snyder K, Andrews PL, Habashi NM, Marx W, Ge L, Wang G, Dean DA, Vodovotz Y, Nieman GF. Airway pressure release ventilation prevents ventilator induced lung injury in normal lungs. JAMA Surg. 2013,Nov; 148(11): 1005-12.


12.      Roy SK, Emr B, Sadowitz B, Gatto LA, Ghosh A, Satalin J, Snyder KP, Ge l, Wang G, Marx W, Dean DA, Andrews PL, Singh A, Scalea T, Habashi NM, Nieman GF. Preemptive application of airway pressure release ventilation (APRV) prevents development of acute respiratory distress syndrome (ARDS) in a rat traumatic hemorrhagic shock model. Shock. 2013;40(3):210-216.


13.      Andrews PL, Shiber JR, Jaruga-Killeen E, Roy SK, Sadowitz B, O’Toole RV, Gatto LA, Nieman GF, Scalea T, Habashi NM. Early application of airway pressure release ventilation may reduce mortality in high-risk trauma patients: A systematic review of observational trauma ARDS literature. J Trauma Acute Care Surg. 2013;75:635-641.


14.      Emr B, Roy SK, Kollisch-Singule M, Gatto LA, Barravecchia M, Lin X, Young JL, Wang G, Liu J, Satalin J, Snyder K, Nieman GF, Dean DA. Electroporation Mediated Gene Delivery of Na+,K+-ATPase and ENaC Subunits to the Lung Attenuates Acute Respiratory Distress Syndrome in a Two-Hit Porcine Model. Shock. 2014;43:16-23.


15.      Kollisch-Singule M, Emr B, Smith B, Roy SK, Jain SV, Satalin J, Snyder K, Andrews PL, Habashi NM, Bates JHT, Marx W, Nieman GF, Gatto LA. Mechanical breath profile of APRV minimizes micro-strain in acute lung injury. JAMA Surg. 2014;13:59.


16.      Kollisch-Singule M, Emr B, Bradford S, Ruiz C, Roy SK, Meng Q, Jain SV, Satalin J, Snyder K, Ghosh A, Marx W, Andrews PL, Habashi NM, Nieman GF, Gatto LA. Airway pressure release ventilation (APRV) reduced conducting airway micro-Strain in lung injury. J Am Coll Surg. 2014;219:968-976.

18.      Andrews PL, Sadowitz B, Kollisch-Singule M, Satalin J, Roy SK, Snyder K, Gatto LA, Nieman GF, Habashi NM. Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury. Intensive Care Med Exp. 2015;3:16.


19.      Roy SK, Meng Q, Sadowitz B, Kollisch-Singule M, Yepuri N, Satalin J, Gatto LA, Nieman GF, Cooney RN, Clark D. Enteral administration of bacteria fermented formula in newborn piglets: A high fidelity model of necrotizing entercolitis (NEC) PLoS One. 2018;13:136.